| Trade date | Director | Volume / Price | Trade value | Trade type |
|---|---|---|---|---|
| 12/07/2023 | John Hawkins | 52,332 @ 8.95p | £4,683.71 | Buy |
| 16/06/2023 | Barbara Staehelin | 150,000 @ 8.15p | £12,225.00 | Buy |
| 16/06/2023 | Iain G Ross | 150,000 @ 8.35p | £12,525.00 | Buy |
| 06/04/2023 | Barbara Staehelin | 50,000 @ 8.70p | £4,350.00 | Buy |
| 03/03/2023 | John Hawkins | 47,668 @ 10.49p | £5,000.37 | Buy |
| 24/02/2023 | Barbara Staehelin | 30,000 @ 10.10p | £3,030.00 | Buy |
| 24/02/2023 | Iain G Ross | 100,000 @ 10.09p | £10,090.00 | Buy |
| 23/01/2023 | Barbara Staehelin | 100,000 @ 10.20p | £10,200.00 | Buy |
| 24/01/2023 | John Hawkins | 100,000 @ 9.88p | £9,880.00 | Buy |
| 23/01/2023 | Iain G Ross | 100,000 @ 9.50p | £9,500.00 | Buy |
| 02/09/2022 | Iain G Ross | 60,000 @ 27.70p | £16,620.00 | Buy |
| 02/09/2022 | Iain G Ross | 30,000 @ 26.00p | £7,800.00 | Buy |
| 02/09/2022 | Iain G Ross | 10,000 @ 25.85p | £2,585.00 | Buy |
| 13/07/2022 | Catherine Isted | 50,000 @ 31.90p | £15,950.00 | Buy |
| 12/07/2022 | Barbara Staehelin | 127,000 @ 30.32p | £38,506.40 | Buy |
| 20/10/2021 | Barbara Staehelin | 43,000 @ 115.00p | £49,450.00 | Buy |
| 18/04/2019 | Christopher Evans | 10,000 @ 228.70p | £22,870.00 | Buy |
| 11/04/2019 | Christopher Evans | 4,500 @ 221.50p | £9,967.50 | Buy |
| 11/04/2019 | Mike Owen | 4,237 @ 236.00p | £9,999.32 | Buy |
| 11/04/2019 | Simon Christopher Cartmell | 7,758 @ 225.55p | £17,498.17 | Buy |
| 11/04/2019 | John Edward Berriman | 80,000 @ 225.00p | £180,000.00 | Buy |
| 27/09/2018 | Michael Hunt | 7,462 @ 67.00p | £4,999.54 | Buy |
| 27/09/2018 | Olav Hellebø | 14,936 @ 66.90p | £9,992.18 | Buy |
| 11/01/2018 | Michael Hunt | 59 @ 1.82p | £1.07 | Placing |
| 07/02/2017 | Michael Hunt | 250,000 @ 2.64p | £6,600.00 | Buy |
| 31/03/2016 | Paul Harper | 0 @ 0.00 | 0.00 | Notification of Holding |
| 31/03/2016 | Christopher Evans | 0 @ 0.00 | 0.00 | Notification of Holding |
| 31/03/2016 | Timothy (Tim) Corn | 0 @ 0.00 | 0.00 | Notification of Holding |
| 31/03/2016 | Simon Christopher Cartmell | 0 @ 0.00 | 0.00 | Notification of Holding |
| 17/02/2016 | Michael Hunt | 1,763,616 @ 2.80p | £49,381.25 | Sell |
| 17/02/2016 | Michael Hunt | 509,554 @ 2.81p | £14,318.47 | Sell |
| 12/02/2016 | Michael Hunt | 594,637 @ 2.80p | £16,649.84 | Sell |
| 11/02/2016 | Michael Hunt | 1,208,333 @ 2.93p | £35,404.16 | Sell |
| 05/02/2016 | Michael Hunt | 1,035,533 @ 3.00p | £31,065.99 | Sell |
| 03/02/2016 | Michael Hunt | 5,361,673 @ 1.00p | £53,616.73 | Exercise of Option |
| 02/02/2016 | John Edward Berriman | 318,476 @ 3.14p | £10,000.15 | Buy |
| 29/01/2015 | Michael Hunt | 161,556 @ 3.10p | £5,008.24 | Buy |
| 29/01/2015 | Olav Hellebø | 322,778 @ 3.10p | £10,006.12 | Buy |
| 25/07/2014 | Michael Hunt | 93,892 @ 3.50p | £3,286.22 | Buy |
| 25/07/2014 | John Sinden | 93,892 @ 3.50p | £3,286.22 | Buy |
| 07/08/2013 | Timothy (Tim) Corn | 200,000 @ 2.50p | £5,000.00 | Placing |
| 07/08/2013 | Paul Harper | 200,000 @ 2.50p | £5,000.00 | Placing |
| 07/08/2013 | Mark Docherty | 600,000 @ 2.50p | £15,000.00 | Placing |
| 07/08/2013 | Simon Christopher Cartmell | 600,000 @ 2.50p | £15,000.00 | Placing |
| 07/08/2013 | John Edward Berriman | 600,000 @ 2.50p | £15,000.00 | Placing |
| 07/08/2013 | John Sinden | 600,000 @ 2.50p | £15,000.00 | Placing |
| 07/08/2013 | Michael Hunt | 800,000 @ 2.50p | £20,000.00 | Placing |
| 07/08/2013 | Bryan Morton | 800,000 @ 2.50p | £20,000.00 | Placing |
| 21/09/2011 | Mark Docherty | 0 @ 0.00 | 0.00 | Notification of Holding |
| 17/12/2010 | Bryan Morton | 90,909 @ 5.50p | £5,000.00 | Placing |
| 17/12/2010 | Paul Harper | 90,909 @ 5.50p | £5,000.00 | Placing |
| 17/12/2010 | Mark Docherty | 45,454 @ 5.50p | £2,499.97 | Placing |
| 17/12/2010 | John Sinden | 90,909 @ 5.50p | £5,000.00 | Placing |
| 17/12/2010 | Michael Hunt | 90,910 @ 5.50p | £5,000.05 | Placing |
| 17/12/2010 | Trevor Jones | 90,909 @ 5.50p | £5,000.00 | Placing |
| 10/12/2010 | Bryan Morton | 0 @ 0.00 | 0.00 | Notification of Holding |
| 10/12/2010 | Paul Harper | 0 @ 0.00 | 0.00 | Notification of Holding |
| 10/12/2010 | Mark Docherty | 0 @ 0.00 | 0.00 | Notification of Holding |
| 10/12/2010 | John Sinden | 0 @ 0.00 | 0.00 | Notification of Holding |
| 10/12/2010 | Michael Hunt | 0 @ 0.00 | 0.00 | Notification of Holding |
| 10/12/2010 | Trevor Jones | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/01/2008 | Paul Harper | 27,600 @ 18.02p | £4,973.52 | Buy |
| 07/01/2008 | Mark Docherty | 28,000 @ 17.80p | £4,984.00 | Buy |
| 07/01/2008 | John Sinden | 28,328 @ 17.65p | £4,999.89 | Buy |
| 07/01/2008 | Michael Hunt | 33,000 @ 18.38p | £6,065.40 | Buy |
| 07/01/2008 | Trevor Jones | 28,000 @ 17.80p | £4,984.00 | Buy |
| 19/12/2006 | John Sinden | 58,580 @ 10.00p | £5,858.00 | Exercise of Option |
| 19/12/2006 | Michael Hunt | 29,500 @ 10.00p | £2,950.00 | Exercise of Option |
| 06/12/2006 | Paul Harper | 25,700 @ 19.50p | £5,011.50 | Buy |
| 06/12/2006 | Trevor Jones | 25,700 @ 19.50p | £5,011.50 | Buy |
| 06/12/2006 | Mark Docherty | 51,400 @ 19.50p | £10,023.00 | Buy |
| 06/12/2006 | John Sinden | 36,000 @ 19.50p | £7,020.00 | Buy |
| 06/12/2006 | Michael Hunt | 51,500 @ 19.50p | £10,042.50 | Buy |
| 25/04/2006 | Trevor Jones | 57,500 @ 13.80p | £7,935.00 | Buy |
| 25/04/2006 | Paul Harper | 57,500 @ 13.75p | £7,906.25 | Buy |
| 25/04/2006 | Michael Hunt | 64,113 @ 13.75p | £8,815.54 | Buy |
| 25/04/2006 | John Sinden | 33,925 @ 13.75p | £4,664.69 | Buy |
| Name | Holding | Percent |
|---|---|---|
| Barbara Staehelin | 500,000 | 0.00% |
| Iain G Ross | 450,000 | 0.00% |
| John Hawkins | 200,000 | 0.00% |
| Mike Owen | 4,237 | 0.00% |
| Institution name | Holding | Percent |
|---|---|---|
| Woodford Investment Management LLP | 5,277,900 | 16.58% |
| Octopus Investments Nominees Limited | 3,347,284 | 5.89% |
| Rosetta Capital VI GP LP | 3,219,519 | 0.00% |
| The Wales Life Sciences Investment Fund LP | 3,000,000 | 5.30% |
| Aviva plc & its subsidiaries | 1,165,378 | 3.68% |
| Majedie Asset Management Limited | 883,636 | 4.96% |