| Trade date | Director | Volume / Price | Trade value | Trade type |
|---|---|---|---|---|
| 29/03/2022 | Jonathan Emms | 15,079 @ 35.73p | £5,387.73 | Buy |
| 29/03/2022 | Ian Johnson | 150,000 @ 36.05p | £54,075.00 | Buy |
| 16/09/2021 | Jonathan Emms | 26,921 @ 37.10p | £9,987.69 | Buy |
| 16/09/2021 | Michael R D Roller | 125,000 @ 37.10p | £46,375.00 | Buy |
| 16/09/2021 | Ian Johnson | 150,000 @ 37.10p | £55,650.00 | Buy |
| 01/04/2021 | Jonathan Emms | 67,928 @ 29.42p | £19,984.42 | Buy |
| 01/04/2021 | Michael R D Roller | 172,500 @ 28.92p | £49,887.00 | Buy |
| 01/04/2021 | Michael R D Roller | 2,500 @ 28.00p | £700.00 | Buy |
| 06/04/2021 | Ian Johnson | 100,000 @ 29.25p | £29,250.00 | Buy |
| 01/04/2021 | Ian Johnson | 100,000 @ 28.50p | £28,500.00 | Buy |
| 04/02/2021 | Jonathan Emms | 600,000 @ 0.00 | 0.00 | Transfer To |
| 09/04/2020 | Michael R D Roller | 200,000 @ 22.68p | £45,360.00 | Buy |
| 09/04/2020 | Jonathan Emms | 300,000 @ 23.20p | £69,600.00 | Buy |
| 09/04/2020 | Ian Johnson | 200,000 @ 22.85p | £45,700.00 | Buy |
| 30/09/2019 | Jonathan Emms | 300,000 @ 16.51p | £49,530.00 | Buy |
| 02/06/2017 | Jean-Jacques Garaud | 77,500 @ 89.11p | £69,060.25 | Sell |
| 02/06/2017 | Jean-Jacques Garaud | 77,500 @ 0.08p | £62.00 | Exercise of Option |
| 18/09/2015 | Charles Swingland | 754,548 @ 320.24p | £2,416,364.52 | Sell |
| 17/09/2015 | Charles Swingland | 9,000 @ 318.72p | £28,684.80 | Sell |
| 16/09/2015 | Charles Swingland | 1,230,000 @ 318.24p | £3,914,352.00 | Sell |
| 27/08/2015 | Charles Swingland | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/05/2015 | Charles Swingland | 0 @ 0.00 | 0.00 | Notification of Holding |
| 27/03/2014 | Rod Hafner | 212,375 @ 0.08p | £169.90 | Exercise of Option |
| 27/03/2014 | Charles Swingland | 535,375 @ 0.08p | £428.30 | Exercise of Option |
| 13/03/2014 | Steven Harris | 0 @ 0.00 | 0.00 | Notification of Holding |
| Name | Holding | Percent |
|---|---|---|
| Jonathan Emms | 709,928 | 0.00% |
| Ian Johnson | 700,000 | 0.00% |
| Michael R D Roller | 500,000 | 0.00% |
| Garry Watts | 477,340 | 0.00% |
| Nicholas Mills | 130,000 | 0.00% |
| Institution name | Holding | Percent |
|---|---|---|
| Richard Griffiths | 111,927,939 | 29.83% |
| The Bank of New York (Nominees) Limited | 87,763,271 | 26.30% |
| Harwood Capital LLP | 77,595,000 | 18.55% |
| AstraZeneca PLC | 71,081,217 | 17.00% |
| Nortrust Nominees Limited | 58,832,384 | 17.60% |
| State Street Nominees Limited | 51,334,357 | 15.40% |
| Imperial Innovations Businesses LLP | 47,355,417 | 14.25% |
| Chase (GA Group) Nominees Limited | 36,606,654 | 9.76% |
| Oryx International Growth Fund Limited | 30,000,000 | 7.99% |
| PH Nominees Limited | 28,324,296 | 8.50% |
| Chase Nominees Limited | 23,185,617 | 7.00% |
| Lombard Odier Asset Management (Europe) Limited | 18,133,419 | 4.81% |
| Neptune Investment Management Limited | 17,909,985 | 4.78% |
| Invesco Limited | 15,660,000 | 4.17% |
| Danske Bank A/S | 13,479,952 | 3.22% |
| CIP Merchant Capital Limited | 12,800,000 | 3.41% |
| Odey Asset Management LLP | 12,688,236 | 4.45% |
| Lansdowne Partners International Limited | 7,893,712 | 4.17% |