| Trade date | Director | Volume / Price | Trade value | Trade type |
|---|---|---|---|---|
| 17/04/2024 | Lisa Anson | 74,500 @ 11.00p | £8,195.00 | Buy |
| 16/04/2024 | Lisa Anson | 115,000 @ 9.38p | £10,787.00 | Buy |
| 11/04/2024 | Lisa Anson | 399,000 @ 7.50p | £29,925.00 | Buy |
| 22/12/2020 | Lisa Anson | 39,998 @ 50.00p | £19,999.00 | Buy |
| 30/06/2020 | Peter Presland | 118,849 @ 25.00p | £29,712.25 | Buy |
| 30/06/2020 | Iain Ross | 53,989 @ 18.50p | £9,987.97 | Buy |
| 30/06/2020 | Iain Ross | 40,000 @ 22.50p | £9,000.00 | Buy |
| 30/06/2020 | Iain Ross | 35,000 @ 19.75p | £6,912.50 | Buy |
| 30/06/2020 | Iain Ross | 86,881 @ 17.25p | £14,986.97 | Buy |
| 25/04/2018 | Iain Ross | 150,000 @ 11.00p | £16,500.00 | Buy |
| 27/12/2017 | Bernhard Kirschbaum | 50,000 @ 21.00p | £10,500.00 | Buy |
| 22/12/2017 | Peter Presland | 120,000 @ 22.00p | £26,400.00 | Buy |
| 22/12/2017 | Peter Presland | 120,000 @ 22.00p | £26,400.00 | Buy |
| 22/12/2017 | Iain Ross | 102,000 @ 20.75p | £21,165.00 | Buy |
| 14/11/2017 | Iain Ross | 348,000 @ 18.04p | £62,779.20 | Buy |
| 05/11/2015 | Peter Jackson | 5,625 @ 80.00p | £4,500.00 | Buy |
| 05/11/2015 | Norman Molyneux | 6,250 @ 80.00p | £5,000.00 | Buy |
| 05/11/2015 | Frank Armstrong | 6,250 @ 80.00p | £5,000.00 | Buy |
| 27/03/2015 | Derek Lindsay | 0 @ 0.00 | 0.00 | Notification of Holding |
| 27/03/2015 | Peter Jackson | 0 @ 0.00 | 0.00 | Notification of Holding |
| Name | Holding | Percent |
|---|---|---|
| Lisa Anson | 751,683 | 0.00% |
| Peter Presland | 146,225 | 0.00% |
| Bernhard Kirschbaum | 50,000 | 0.00% |
| Institution name | Holding | Percent |
|---|---|---|
| Funds managed by Redmile Group LLC | 276,890,319 | 71.18% |
| Redmile Group, LLC | 276,890,319 | 71.18% |
| Sofinnova Crossover I SLP | 51,948,307 | 13.35% |
| Seneca Partners Limited | 15,792,781 | 12.49% |
| Invus Public Equities L.P. | 15,203,815 | 3.91% |
| Tang Capital Partners, LP | 11,710,000 | 3.01% |
| Lanstead Capital LP | 9,625,000 | 7.61% |
| Jon Moulton | 9,325,000 | 7.37% |
| Aviva plc & its subsidiaries | 8,628,394 | 6.93% |
| AXA Framlington | 6,400,000 | 9.85% |
| WCS Nominees Limited | 6,256,416 | 9.60% |
| Paul Blackmore and Thekla Blackmore | 5,100,000 | 4.03% |
| Graham Edwards | 3,999,900 | 6.20% |
| Alderley Park Holdings Limited | 3,605,084 | 3.90% |
| NW VCF HF LLP | 3,506,775 | 5.40% |