SANTANDER UK GROUP HOLDINGS PLC

(incorporated in England and Wales with registered number 8700698)

SANTANDER UK PLC

(incorporated in England and Wales with registered number 2294747)

€30,000,000,000 EURO MEDIUM TERM NOTE PROGRAMME

PUBLICATION OF PROSPECTUS

NOTICE IS HEREBY GIVEN that certain legal and regulatory updates and amendments have been made to the prospectus relating to the €30,000,000,000 Euro Medium Term Note Programme with Santander UK Group Holdings plc and Santander UK plc as issuers (the "Prospectus"). The Prospectus is dated 5 April 2024 and has been approved by the Financial Conduct Authority in its capacity as competent authority under the Financial Services and Markets Act 2000 and is available for viewing by clicking on or pasting the following URL:

http://www.rns-pdf.londonstockexchange.com/rns/5804J_1-2024-4-5.pdf

A copy of the Prospectus listed above has also been submitted to the National Storage Mechanism and will shortly be available for inspection at https://data.fca.org.uk/#/nsm/nationalstoragemechanism.

For further information, please contact:

Medium Term Funding
Santander UK Group Holdings plc
2 Triton Square
Regent's Place
London NW1 3AN

Email: mtf@santander.co.uk

DISCLAIMER - INTENDED ADDRESSEES

Please note that the information contained in the Prospectus may be addressed to and/or targeted at persons who are residents of particular countries (specified in the Prospectus) only and is not intended for use and should not be relied upon by any person outside these countries and/or to whom the offer contained in the Prospectus is not addressed.  Prior to relying on the information contained in the Prospectus, you must ascertain from the Prospectus whether or not you are part of the intended addressees of the information contained therein.

Your right to access this service is conditional upon complying with the above requirement.

The Prospectus on this website does not constitute an offer of securities for sale in the United States. The securities described herein have not been, and will not be, registered under the U.S. Securities Act of 1933, as amended (the "Securities Act"), or under any relevant securities laws of any state of the United States of America, and may not be offered or sold in, the United States of America, or to, or for the benefit of, U.S. persons (as defined in Regulation S of the Securities Act), unless the securities are registered under the Securities Act or an exemption from the registration requirements of the Securities Act is available.