| Trade date | Director | Volume / Price | Trade value | Trade type |
|---|---|---|---|---|
| 08/11/2024 | Angela Rushforth | 835 @ 178.00p | £1,486.30 | Buy |
| 08/11/2024 | Will Truman | 1,224 @ 178.00p | £2,178.72 | Buy |
| 08/11/2024 | Iraj Amiri | 1,187 @ 178.00p | £2,112.86 | Buy |
| 08/11/2024 | Alison Littley | 1,402 @ 178.00p | £2,495.56 | Buy |
| 06/08/2024 | Angela Rushforth | 1,141 @ 145.00p | £1,654.45 | Buy |
| 06/08/2024 | Will Truman | 1,264 @ 145.00p | £1,832.80 | Buy |
| 06/08/2024 | Iraj Amiri | 1,456 @ 145.00p | £2,111.20 | Buy |
| 06/08/2024 | Alison Littley | 1,524 @ 145.00p | £2,209.80 | Buy |
| 06/08/2024 | Derek Mapp | 3,650 @ 145.00p | £5,292.50 | Buy |
| 07/05/2024 | Angela Rushforth | 1,329 @ 135.00p | £1,794.15 | Buy |
| 07/05/2024 | Will Truman | 1,211 @ 135.00p | £1,634.85 | Buy |
| 07/05/2024 | Iraj Amiri | 1,519 @ 135.00p | £2,050.65 | Buy |
| 07/05/2024 | Kate Allum | 1,527 @ 135.00p | £2,061.45 | Buy |
| 07/05/2024 | Alison Littley | 1,483 @ 135.00p | £2,002.05 | Buy |
| 07/05/2024 | Frank Nelson | 1,519 @ 135.00p | £2,050.65 | Buy |
| 07/05/2024 | Derek Mapp | 3,817 @ 135.00p | £5,152.95 | Buy |
| 26/03/2024 | Iraj Amiri | 54,892 @ 119.50p | £65,595.94 | Buy |
| 09/02/2024 | Will Truman | 1,206 @ 125.00p | £1,507.50 | Buy |
| 09/02/2024 | Iraj Amiri | 1,617 @ 125.00p | £2,021.25 | Buy |
| 09/02/2024 | Kate Allum | 1,395 @ 125.00p | £1,743.75 | Buy |
| 09/02/2024 | Alison Littley | 1,300 @ 125.00p | £1,625.00 | Buy |
| 09/02/2024 | Frank Nelson | 1,617 @ 125.00p | £2,021.25 | Buy |
| 09/02/2024 | Derek Mapp | 4,067 @ 125.00p | £5,083.75 | Buy |
| 28/11/2023 | Michael Scott | 67,582 @ 118.40p | £80,017.09 | Sell |
| 28/11/2023 | Michael Scott | 143,069 @ 0.00 | 0.00 | Exercise of Option |
| 13/11/2023 | Will Truman | 862 @ 115.00p | £991.30 | Buy |
| 13/11/2023 | Iraj Amiri | 1,758 @ 115.00p | £2,021.70 | Buy |
| 13/11/2023 | Kate Allum | 1,473 @ 115.00p | £1,693.95 | Buy |
| 13/11/2023 | Alison Littley | 1,370 @ 115.00p | £1,575.50 | Buy |
| 13/11/2023 | Frank Nelson | 1,758 @ 115.00p | £2,021.70 | Buy |
| 13/11/2023 | Derek Mapp | 4,420 @ 115.00p | £5,083.00 | Buy |
| 01/11/2023 | Derek Mapp | 100,000 @ 108.25p | £108,250.00 | Buy |
| 13/10/2023 | Derek Mapp | 100,000 @ 111.00p | £111,000.00 | Buy |
| 20/09/2023 | Michael Scott | 16,864 @ 118.00p | £19,899.52 | Buy |
| 20/09/2023 | Frank Nelson | 18,250 @ 114.00p | £20,805.00 | Buy |
| 20/09/2023 | Darren Waters | 42,161 @ 118.00p | £49,749.98 | Buy |
| 20/09/2023 | Frank Nelson | 18,250 @ 114.00p | £20,805.00 | Buy |
| 08/08/2023 | Iraj Amiri | 1,821 @ 111.00p | £2,021.31 | Buy |
| 08/08/2023 | Kate Allum | 1,741 @ 111.00p | £1,932.51 | Buy |
| 08/08/2023 | Alison Littley | 1,624 @ 111.00p | £1,802.64 | Buy |
| 08/08/2023 | Frank Nelson | 1,901 @ 111.00p | £2,110.11 | Buy |
| 08/08/2023 | Derek Mapp | 4,580 @ 111.00p | £5,083.80 | Buy |
| 09/05/2023 | Iraj Amiri | 1,349 @ 130.00p | £1,753.70 | Buy |
| 09/05/2023 | Iraj Amiri | 1,349 @ 130.00p | £1,753.70 | Buy |
| 09/05/2023 | Kate Allum | 1,204 @ 130.00p | £1,565.20 | Buy |
| 09/05/2023 | Alison Littley | 1,288 @ 130.00p | £1,674.40 | Buy |
| 09/05/2023 | Frank Nelson | 1,724 @ 130.00p | £2,241.20 | Buy |
| 09/05/2023 | Derek Mapp | 3,910 @ 130.00p | £5,083.00 | Buy |
| 21/04/2023 | Derek Mapp | 100,000 @ 127.50p | £127,500.00 | Buy |
| 16/03/2023 | Michael Scott | 13,944 @ 142.00p | £19,800.48 | Buy |
| 16/03/2023 | Derek Mapp | 68,000 @ 142.00p | £96,560.00 | Buy |
| 21/06/2022 | Derek Mapp | 91,000 @ 189.50p | £172,445.00 | Buy |
| 12/05/2022 | Michael Scott | 12,891 @ 192.00p | £24,750.72 | Buy |
| 12/05/2022 | Mark Kelly | 38,674 @ 192.00p | £74,254.08 | Buy |
| 22/04/2021 | Michael Scott | 21,483 @ 0.00 | 0.00 | Exercise of Option |
| 22/04/2021 | Mark Kelly | 29,822 @ 0.00 | 0.00 | Exercise of Option |
| 25/11/2020 | Michael Scott | 6,743 @ 212.50p | £14,328.88 | Sell |
| 25/11/2020 | Mark Kelly | 24,115 @ 212.50p | £51,244.38 | Sell |
| 25/11/2020 | Michael Scott | 14,273 @ 0.00 | 0.00 | Exercise of Option |
| 25/11/2020 | Mark Kelly | 51,049 @ 0.00 | 0.00 | Exercise of Option |
| 14/10/2020 | Michael Scott | 11,029 @ 163.20p | £17,999.33 | Exercise of Option |
| 09/09/2020 | Mark Kelly | 11,029 @ 163.20p | £17,999.33 | Exercise of Option |
| 01/04/2020 | Martyn Coffey | 5,714 @ 175.00p | £9,999.50 | Buy |
| 01/04/2020 | Frank Nelson | 5,714 @ 175.00p | £9,999.50 | Buy |
| 01/04/2020 | Robert (Bob) Lawson | 14,285 @ 175.00p | £24,998.75 | Buy |
| 01/04/2020 | Michael Scott | 5,714 @ 175.00p | £9,999.50 | Buy |
| 01/04/2020 | Mark Kelly | 14,285 @ 175.00p | £24,998.75 | Buy |
| 21/12/2017 | Martyn Coffey | 5,000 @ 2.16p | £108.00 | Buy |
| 05/09/2017 | Mark Kelly | 58,334 @ 235.00p | £137,084.90 | Sell |
| 05/09/2017 | Mark Kelly | 123,864 @ 0.00 | 0.00 | Buy |
| 15/03/2017 | Michael Scott | 14,215 @ 210.00p | £29,851.50 | Buy |
| 15/03/2017 | Robert (Bob) Lawson | 14,215 @ 210.00p | £29,851.50 | Buy |
| 24/08/2016 | Robert (Bob) Lawson | 15,739 @ 170.69p | £26,864.90 | Buy |
| 24/08/2016 | Mark Kelly | 43,939 @ 170.69p | £74,999.48 | Buy |
| 23/08/2016 | Patrick Kalverboer | 30,000 @ 162.00p | £48,600.00 | Buy |
| 04/03/2015 | Frank Nelson | 0 @ 0.00 | 0.00 | Notification of Holding |
| 04/03/2015 | Robert (Bob) Lawson | 0 @ 0.00 | 0.00 | Notification of Holding |
| 04/03/2015 | Patrick Kalverboer | 0 @ 0.00 | 0.00 | Notification of Holding |
| 04/03/2015 | Martyn Coffey | 0 @ 0.00 | 0.00 | Notification of Holding |
| 04/03/2015 | Matthew Edwards | 0 @ 0.00 | 0.00 | Notification of Holding |
| 04/03/2015 | Patrick Bateman | 0 @ 0.00 | 0.00 | Notification of Holding |
| Name | Holding | Percent |
|---|---|---|
| Derek Mapp | 487,864 | 0.00% |
| Michael Scott | 186,426 | 0.00% |
| Iraj Amiri | 67,357 | 0.00% |
| Darren Waters | 42,161 | 0.00% |
| Alison Littley | 11,386 | 0.00% |
| Will Truman | 5,767 | 0.00% |
| Angela Rushforth | 1,976 | 0.00% |
| Institution name | Holding | Percent |
|---|---|---|
| Soros Fund Management | 18,337,234 | 16.40% |
| Aberforth Partners | 16,380,108 | 16.00% |
| Perpetual Limited | 11,315,996 | 11.01% |
| J O Hambro Capital Management Limited | 11,092,556 | 9.90% |
| SFM UK Management LLP | 9,702,646 | 9.27% |
| BlackRock Investment Managers (UK) | 9,291,081 | 9.29% |
| The Wellcome Trust Limited | 8,415,301 | 8.02% |
| Huntington Management, LLC | 7,750,775 | 6.90% |
| Canaccord Genuity Group Inc | 6,361,026 | 6.36% |
| 1607 Capital Partners, LLC | 5,775,000 | 5.78% |
| Chelverton Asset Management Limited | 5,575,000 | 5.07% |
| Alantra EQMC Asset Management, SGIIC, S.A. | 5,413,717 | 4.98% |
| Santander Asset Management UK | 5,267,323 | 4.77% |
| Schroder Investment Management | 5,145,288 | 4.59% |
| Columbia Threadneedle Investments | 5,020,929 | 4.50% |
| ACR Alpine Capital Research | 4,850,660 | 4.30% |
| Allianz Global Investors | 4,108,178 | 3.70% |
| Premier Miton Investors | 3,633,000 | 3.20% |
| Royal London Asset Management | 3,549,000 | 3.20% |
| Henderson Global Investors | 3,375,404 | 3.00% |