| Trade date | Director | Volume / Price | Trade value | Trade type |
|---|---|---|---|---|
| 10/04/2025 | Peter Presland | 3,398,553 @ 0.44p | £14,953.63 | Buy |
| 01/04/2025 | Paul Stockdale | 791,176 @ 0.45p | £3,560.29 | Buy |
| 01/04/2025 | Paul Stockdale | 791,176 @ 0.45p | £3,560.29 | Sell |
| 28/11/2024 | David Holbrook | 49,653 @ 1.25p | £620.66 | Transfer From |
| 28/11/2024 | Matthew Wakefield | 98,118 @ 1.25p | £1,226.48 | Transfer From |
| 28/11/2024 | Paul Stockdale | 179,847 @ 1.25p | £2,248.09 | Transfer From |
| 28/11/2024 | Alexandre Akoulitchev | 492,682 @ 1.25p | £6,158.53 | Transfer From |
| 28/11/2024 | Jon Burrows | 492,682 @ 125.00p | £615,852.50 | Transfer From |
| 28/10/2024 | David Holbrook | 49,653 @ 1.30p | £645.49 | Buy |
| 28/10/2024 | Matthew Wakefield | 98,118 @ 1.30p | £1,275.53 | Buy |
| 28/10/2024 | Paul Stockdale | 179,847 @ 1.30p | £2,338.01 | Buy |
| 28/10/2024 | Alexandre Akoulitchev | 194,263 @ 1.30p | £2,525.42 | Buy |
| 28/10/2024 | Jon Burrows | 492,682 @ 1.30p | £6,404.87 | Buy |
| 10/11/2023 | Stephen Charles Diggle | 125,000 @ 33.90p | £42,375.00 | Sell |
| 02/11/2023 | Matthew Wakefield | 200,000 @ 0.00 | 0.00 | Transfer To |
| 02/11/2023 | Matthew Wakefield | 94,000 @ 0.00 | 0.00 | Transfer To |
| 18/10/2023 | Stephen Charles Diggle | 777,000 @ 38.30p | £297,591.00 | Sell |
| 04/10/2023 | Stephen Charles Diggle | 115,000 @ 45.20p | £51,980.00 | Sell |
| 26/01/2023 | Stephen Charles Diggle | 443,673 @ 14.75p | £65,441.77 | Buy |
| 22/02/2023 | Jon Burrows | 7,548 @ 0.20p | £15.10 | Buy |
| 22/02/2023 | Jon Burrows | 40,588 @ 0.20p | £81.18 | Buy |
| 22/02/2023 | Jon Burrows | 1,864 @ 0.19p | £3.54 | Buy |
| 26/01/2023 | Stephen Charles Diggle | 200,000 @ 14.70p | £29,400.00 | Buy |
| 26/01/2023 | Stephen Charles Diggle | 143,673 @ 14.80p | £21,263.60 | Buy |
| 11/11/2022 | Stephen Charles Diggle | 50,000 @ 18.00p | £9,000.00 | Buy |
| 10/11/2022 | Stephen Charles Diggle | 112,051 @ 18.20p | £20,393.28 | Buy |
| 30/06/2022 | Jon Burrows | 41,067 @ 13.50p | £5,544.05 | Buy |
| 30/06/2022 | Jon Burrows | 23,933 @ 13.45p | £3,218.99 | Buy |
| 20/05/2022 | Matthew Wakefield | 25,000 @ 17.40p | £4,350.00 | Buy |
| 06/04/2022 | Stephen Charles Diggle | 400,000 @ 18.80p | £75,200.00 | Buy |
| 06/04/2022 | Stephen Charles Diggle | 200,000 @ 18.50p | £37,000.00 | Buy |
| 06/04/2022 | Matthew Wakefield | 25,000 @ 16.40p | £4,100.00 | Buy |
| 06/04/2022 | Matthew Wakefield | 25,000 @ 18.90p | £4,725.00 | Buy |
| 05/04/2022 | Jon Burrows | 20,000 @ 17.92p | £3,584.00 | Buy |
| 06/04/2022 | Paul Stockdale | 30,000 @ 17.80p | £5,340.00 | Buy |
| 03/03/2022 | Jon Burrows | 15,000 @ 22.20p | £3,330.00 | Buy |
| 02/03/2022 | Stephen Charles Diggle | 400,000 @ 22.20p | £88,800.00 | Buy |
| 01/03/2022 | Stephen Charles Diggle | 143,997 @ 22.40p | £32,255.33 | Buy |
| 07/02/2022 | Stephen Charles Diggle | 10,000 @ 28.50p | £2,850.00 | Buy |
| 08/02/2022 | Stephen Charles Diggle | 7,248 @ 28.50p | £2,065.68 | Buy |
| 07/02/2022 | Jon Burrows | 50,000 @ 30.00p | £15,000.00 | Buy |
| 26/01/2022 | Paul Stockdale | 35,000 @ 27.20p | £9,520.00 | Buy |
| 25/01/2022 | Matthew Wakefield | 25,000 @ 27.00p | £6,750.00 | Buy |
| 25/01/2022 | Matthew Wakefield | 50,000 @ 29.34p | £14,670.00 | Buy |
| 25/01/2022 | Alexandre Akoulitchev | 100,000 @ 29.60p | £29,600.00 | Buy |
| 24/12/2021 | Matthew Wakefield | 31,187 @ 33.40p | £10,416.46 | Buy |
| 09/12/2021 | Stephen Charles Diggle | 50,000 @ 37.10p | £18,550.00 | Buy |
| 01/12/2021 | Paul Stockdale | 12,000 @ 41.80p | £5,016.00 | Buy |
| 22/11/2021 | Stephen Charles Diggle | 100,000 @ 41.20p | £41,200.00 | Buy |
| 19/11/2021 | Stephen Charles Diggle | 99,471 @ 41.90p | £41,678.35 | Buy |
| 18/11/2021 | Stephen Charles Diggle | 98,533 @ 42.00p | £41,383.86 | Buy |
| 16/11/2021 | Stephen Charles Diggle | 2,500,000 @ 45.50p | £1,137,500.00 | Buy |
| 15/06/2021 | Paul Stockdale | 8,000 @ 56.24p | £4,499.20 | Buy |
| 29/06/2020 | Peter Pack | 15,000 @ 62.00p | £9,300.00 | Buy |
| 22/06/2020 | Stephen Charles Diggle | 60,000 @ 59.33p | £35,598.00 | Buy |
| 16/06/2020 | Paul Stockdale | 5,000 @ 64.95p | £3,247.50 | Buy |
| 14/05/2020 | Stephen Charles Diggle | 3,000 @ 63.00p | £1,890.00 | Buy |
| 12/05/2020 | Stephen Charles Diggle | 30,000 @ 67.50p | £20,250.00 | Buy |
| 21/04/2020 | Stephen Charles Diggle | 10,000 @ 52.00p | £5,200.00 | Buy |
| 17/04/2020 | Stephen Charles Diggle | 8,397 @ 52.00p | £4,366.44 | Buy |
| 16/04/2020 | Stephen Charles Diggle | 7,805 @ 50.00p | £3,902.50 | Buy |
| 16/04/2020 | Stephen Charles Diggle | 10,000 @ 13.10p | £1,310.00 | Buy |
| 14/04/2020 | Stephen Charles Diggle | 10,000 @ 50.50p | £5,050.00 | Buy |
| 09/04/2020 | Stephen Charles Diggle | 10,000 @ 53.00p | £5,300.00 | Buy |
| 08/04/2020 | Stephen Charles Diggle | 10,000 @ 52.00p | £5,200.00 | Buy |
| 07/04/2020 | Stephen Charles Diggle | 22,002 @ 52.50p | £11,551.05 | Buy |
| 20/03/2020 | Stephen Charles Diggle | 26,000 @ 56.00p | £14,560.00 | Buy |
| 19/03/2020 | Stephen Charles Diggle | 5,000 @ 52.00p | £2,600.00 | Buy |
| 19/03/2020 | Christian Gurth Hoyer Millar | 2,000 @ 49.66p | £993.20 | Buy |
| 19/03/2020 | Christian Gurth Hoyer Millar | 4,000 @ 49.00p | £1,960.00 | Buy |
| 16/03/2020 | Christian Gurth Hoyer Millar | 4,000 @ 66.50p | £2,660.00 | Buy |
| 16/03/2020 | Stephen Charles Diggle | 13,443 @ 63.80p | £8,576.63 | Buy |
| 28/02/2020 | Stephen Charles Diggle | 150,000 @ 85.20p | £127,800.00 | Buy |
| 27/02/2020 | Stephen Charles Diggle | 2,594 @ 84.50p | £2,191.93 | Buy |
| 25/02/2020 | Stephen Charles Diggle | 38,963 @ 79.20p | £30,858.70 | Buy |
| 10/12/2019 | Stephen Charles Diggle | 18,309 @ 104.00p | £19,041.36 | Buy |
| 10/09/2019 | Stephen Charles Diggle | 10,000 @ 85.00p | £8,500.00 | Buy |
| 09/09/2019 | Stephen Charles Diggle | 11,406 @ 87.00p | £9,923.22 | Buy |
| 06/09/2019 | Stephen Charles Diggle | 10,000 @ 89.00p | £8,900.00 | Buy |
| 05/09/2019 | Stephen Charles Diggle | 10,500 @ 90.00p | £9,450.00 | Buy |
| 02/09/2019 | Stephen Charles Diggle | 10,000 @ 90.00p | £9,000.00 | Buy |
| 30/08/2019 | Paul Stockdale | 2,186 @ 91.25p | £1,994.73 | Buy |
| 30/08/2019 | Christian Gurth Hoyer Millar | 14,000 @ 85.51p | £11,971.40 | Buy |
| 30/08/2019 | Stephen Charles Diggle | 6,730 @ 92.00p | £6,191.60 | Buy |
| 28/08/2019 | Stephen Charles Diggle | 4,500 @ 90.00p | £4,050.00 | Buy |
| 27/08/2019 | Stephen Charles Diggle | 40,000 @ 90.00p | £36,000.00 | Buy |
| 14/08/2019 | Stephen Charles Diggle | 13,000 @ 103.00p | £13,390.00 | Buy |
| 13/08/2019 | Stephen Charles Diggle | 15,000 @ 105.00p | £15,750.00 | Buy |
| 31/07/2019 | Stephen Charles Diggle | 10,000 @ 115.00p | £11,500.00 | Buy |
| 30/07/2019 | Stephen Charles Diggle | 6,256 @ 115.00p | £7,194.40 | Buy |
| 24/07/2019 | Stephen Charles Diggle | 2,786 @ 120.00p | £3,343.20 | Buy |
| 08/07/2019 | Stephen Charles Diggle | 10,000 @ 125.00p | £12,500.00 | Buy |
| 08/07/2019 | Christian Gurth Hoyer Millar | 2,000 @ 128.85p | £2,577.00 | Buy |
| 08/07/2019 | Christian Gurth Hoyer Millar | 2,000 @ 126.94p | £2,538.80 | Buy |
| 05/07/2019 | Christian Gurth Hoyer Millar | 2,000 @ 126.09p | £2,521.80 | Buy |
| 05/07/2019 | Christian Gurth Hoyer Millar | 3,000 @ 125.00p | £3,750.00 | Buy |
| 05/07/2019 | Paul Stockdale | 5,830 @ 128.50p | £7,491.55 | Buy |
| 05/07/2019 | Paul Stockdale | 1,984 @ 126.00p | £2,499.84 | Buy |
| 05/07/2019 | Christian Gurth Hoyer Millar | 5,000 @ 122.96p | £6,148.00 | Buy |
| 05/06/2019 | Stephen Charles Diggle | 9,300 @ 137.00p | £12,741.00 | Buy |
| Name | Holding | Percent |
|---|---|---|
| Stephen Charles Diggle | 27,431,756 | 13.00% |
| Alexandre Akoulitchev | 6,990,027 | 0.00% |
| Peter Presland | 3,398,553 | 0.00% |
| Paul Stockdale | 3,077,919 | 0.00% |
| Jon Burrows | 1,285,364 | 0.00% |
| David Holbrook | 99,306 | 0.00% |
| Institution name | Holding | Percent |
|---|---|---|
| Vulpes Life Sciences Fund | 251,876,178 | 12.87% |
| Unicorn Asset Management Limited | 145,131,526 | 7.41% |
| Sankofa Strategic Equity Fund Limited | 128,521,716 | 6.57% |
| Arbuthnot Latham (Nominees) Limited | 74,250,303 | 3.79% |
| William Henry Salomon | 60,000,000 | 3.07% |
| Odey Funds | 26,945,092 | 18.37% |
| Lombard Odier Asset Management (Europe) Limited | 15,568,816 | 4.99% |
| Seneca Partners Limited | 9,978,822 | 4.93% |
| Armistice Capital LLC | 7,791,803 | 7.76% |
| Investec Wealth & Investment Limited | 7,319,886 | 4.99% |
| The Chancellor, Masters and Scholars of the University of Oxford | 5,724,476 | 3.90% |
| GL Healthcare Investment L.P. | 4,688,000 | 3.20% |
| PHILIPPA MARGARET HOYER MILLAR | 4,473,140 | 3.05% |