| Trade date | Director | Volume / Price | Trade value | Trade type |
|---|---|---|---|---|
| 08/10/2024 | Christopher H B Mills | 500,000 @ 9.00p | £45,000.00 | Placing |
| 07/10/2024 | Christopher H B Mills | 83,696 @ 8.00p | £6,695.68 | Sell |
| 08/02/2023 | Christopher H B Mills | 346,375 @ 90.00p | £311,737.50 | Placing |
| 31/03/2022 | Timothy Scannell | 68,964 @ 276.00p | £190,340.64 | Placing |
| 31/03/2022 | Ann E. Berman | 27,586 @ 276.00p | £76,137.36 | Placing |
| 31/03/2022 | Christopher H B Mills | 551,724 @ 276.00p | £1,522,758.24 | Placing |
| 16/12/2021 | Ann E. Berman | 3,000 @ $14.00 | $42,000.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 200 @ $7.88 | $1,576.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 200 @ $7.75 | $1,550.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 180 @ $8.00 | $1,440.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 200 @ $7.80 | $1,560.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 50 @ $8.01 | $400.50 | Buy |
| 10/12/2021 | James Renwick McCullough | 180 @ $8.00 | $1,440.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 100 @ $7.75 | $775.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 100 @ $7.75 | $775.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 60 @ $7.88 | $472.80 | Buy |
| 10/12/2021 | James Renwick McCullough | 100 @ $7.90 | $790.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 200 @ $7.86 | $1,572.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 100 @ $7.93 | $793.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 400 @ $7.93 | $3,172.00 | Buy |
| 10/12/2021 | James Renwick McCullough | 400 @ $7.92 | $3,168.00 | Buy |
| 09/12/2021 | James Renwick McCullough | 1,000 @ $7.80 | $7,800.00 | Buy |
| 09/12/2021 | James Renwick McCullough | 400 @ $8.02 | $3,208.00 | Buy |
| 09/12/2021 | James Renwick McCullough | 300 @ $7.53 | $2,259.00 | Buy |
| 09/12/2021 | James Renwick McCullough | 66 @ $7.50 | $495.00 | Buy |
| 09/12/2021 | James Renwick McCullough | 240 @ $7.55 | $1,812.00 | Buy |
| 08/12/2021 | James Renwick McCullough | 500 @ $7.50 | $3,750.00 | Buy |
| 08/12/2021 | James Renwick McCullough | 1,000 @ $7.55 | $7,550.00 | Buy |
| 08/12/2021 | James Renwick McCullough | 200 @ $7.43 | $1,486.00 | Buy |
| 08/12/2021 | James Renwick McCullough | 200 @ $7.52 | $1,504.00 | Buy |
| 31/08/2021 | James Sterling | 6,000 @ 1,444.41p | £86,664.60 | Sell |
| 10/08/2021 | James Sterling | 12,000 @ $14.07 | $168,840.00 | Exercise of Option |
| 12/08/2021 | James Sterling | 12,000 @ $14.00 | $168,000.00 | Sell |
| 05/08/2021 | James Sterling | 6,000 @ $13.98 | $83,880.00 | Sell |
| 05/08/2021 | James Sterling | 6,000 @ $14.00 | $84,000.00 | Sell |
| 03/08/2021 | James Sterling | 12,000 @ $14.30 | $171,600.00 | Sell |
| 29/07/2021 | James Sterling | 12,000 @ $16.49 | $197,880.00 | Sell |
| 29/07/2021 | James Sterling | 12,000 @ 1,515.00p | £181,800.00 | Sell |
| 22/07/2021 | James Sterling | 6,000 @ 1,397.50p | £83,850.00 | Sell |
| 22/07/2021 | James Sterling | 12,000 @ 0.00 | 0.00 | Sell |
| 25/06/2021 | Christopher H B Mills | 6,100 @ 1,125.00p | £68,625.00 | Sell |
| 18/06/2021 | Christopher H B Mills | 17,000 @ 1,135.29p | £192,999.30 | Sell |
| 24/05/2021 | James Renwick McCullough | 4,524 @ $16.14 | $73,017.36 | Sell |
| 21/05/2021 | James Renwick McCullough | 16,400 @ $16.12 | $264,368.00 | Sell |
| 20/05/2021 | James Renwick McCullough | 29,076 @ $16.16 | $469,868.16 | Sell |
| 19/05/2021 | James Renwick McCullough | 30,000 @ $15.23 | $456,900.00 | Sell |
| 18/04/2021 | James Renwick McCullough | 2,298,958 @ $6.68 | $15,357,039.44 | Sell |
| 18/04/2021 | James Renwick McCullough | 255,440 @ 0.00 | 0.00 | Transfer To |
| 20/12/2018 | Christopher H B Mills | 3,168 @ 112.00p | £3,548.16 | Buy |
| 19/12/2018 | Christopher H B Mills | 5,970 @ 103.00p | £6,149.10 | Buy |
| 06/11/2018 | James Renwick McCullough | 16,150 @ 120.00p | £19,380.00 | Buy |
| 07/11/2018 | James Sterling | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/11/2018 | Richard Evans | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/11/2018 | Julian Baines | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/11/2018 | James Renwick McCullough | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/11/2018 | Christopher H B Mills | 0 @ 0.00 | 0.00 | Notification of Holding |
| 07/11/2018 | Christopher H B Mills | 0 @ 0.00 | 0.00 | Notification of Holding |
| Name | Holding | Percent |
|---|---|---|
| Christopher H B Mills | 14,609,946 | 7.00% |
| James Renwick McCullough | 2,746,386 | 3.00% |
| Fergus Fleming | 569,481 | 0.00% |
| Institution name | Holding | Percent |
|---|---|---|
| CVI Holdings, LLC | 33,000,000 | 9.96% |
| Ruffer LLP | 28,500,000 | 8.54% |
| Unicorn Asset Management Limited | 18,955,777 | 5.68% |
| Harwood Capital LLP | 14,609,946 | 4.41% |
| Polar Capital, LLP | 13,866,061 | 7.95% |
| Icahn School of Medicine at Mount Sinai | 10,750,926 | 14.90% |
| Jefferson River Capital LLC | 8,294,932 | 8.86% |
| Mount Sinai | 8,018,986 | 14.90% |
| Gilder Gagnon Howe and Co LLC | 6,042,634 | 8.40% |
| Forest Nominees Limited | 4,001,187 | 3.34% |
| Lombard Odier & Co Ltd | 2,952,334 | 4.97% |
| Amati Global Investors | 2,455,247 | 3.40% |
| Fidelity Investment International | 2,173,851 | 3.00% |